DNBSEQ-G400 FluoXpert

Unleash the Power of Multi-Omics

Genomics, Transcriptomics, and Proteomics in One System

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DNBSEQ-G400 FluoXpert

Unleash the Power of Multi-Omics

Genomics, Transcriptomics, and Proteomics in One System

Compatible

Works with off-the-shelf antibodies, no conjugation needed.

Fully Automated

High-quality results across staining, imaging, and sequencing.

Versatile

Perfect for FFPE and frozen samples, with scalable 6- to 24-plex* staining.

Genomics, Transcriptomics, and Proteomics in One System

The DNBSEQ-G400 FluoXpert is a high-throughput sequencing platform uniquely incorporating multiplex immunofluorescence (mIF) staining capabilities. As a sequencer, it delivers up to 1440Gb of data per run with superior accuracy, while its integrated staining module enables the detection of up to 24 protein targets on a single tissue section.

Its automated workflow seamlessly transitions between sequencing and staining functions, streamlining genomic analysis alongside tissue visualization for comprehensive tumor classification, disease prognosis, and microenvironment characterization.

The platform’s dual functionality conserves valuable samples by allowing molecular and protein analysis from the same instrument, with high-resolution imaging at 360 nm/pixel resolution and efficient reagent usage.

Learn more about DNBSEQ-G400 for sequencing.

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The DNBSEQ-G400 FluoXpert system includes a multiplex immunofluorescence reagent kit that supports both frozen and FFPE samples, providing compatibility across diverse sample types. Its streamlined integration with commercially available antibodies removes the need for complex conjugation processes, saving time and effort. FluoXpert delivers results comparable to the gold standard of IHC, making it a versatile tool for various proteomics applications. 

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No significance is observed between mIF and the gold standard IHC 

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FluoXpert Flow Cell Types

SS Staining Flow Cell

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Solo Small (SS)

Suitable for small tissue samples such as percutaneous biopsy. Even faster staining speed.

Optimal Throughput: 20 sections/week
Highest Throughput: 84 sections/week
Scanning Region: 15 mm x 15 mm

SL Staining Flow Cell

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Solo Large (SL)

Suitable for larger tissue samples such as tonsils and tumor. Larger scanning area for larger view.

Optimal Throughput: 20 sections/week
Highest Throughput: 84 sections/week
Scanning Region: 15 mm x 20 mm

DL Staining Flow Cell

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Dual Large (DL)

Suitable for two tissue sections on one slide. Batch staining for less reagent used.

Optimal Throughput: 40 sections/week
Highest Throughput: 140 sections/week
Scanning Region: 15 mm x 20 mm x 2

Performance Parameters

Sample TypeFlow Cell Type# of FC per RunData Output per WeekRun Time
FFPE, Frozen tissuesSS, SL220 sections4-5 hr (6-plex)
10.5 hr-12.8 hr (24-plex)
DL240 sections

Specifications are based on Complete Genomics E. coli control library using Complete Genomics standard library preparation method. Actual performance may vary based on library type, library quality, insert size, and other experimental factors.

Ordering Information

CategoryProductCat. No.
InstrumentDNBSEQ-G400 FluoXpert900-000938-00
Sequencing ReagentsDNBSEQ-G400 SS 6P mIF Set940-002132-00
DNBSEQ-G400 SL 6P mIF Set940-002133-00
DNBSEQ-G400 DL 6P mIF Set940-002134-00
SoftwareFluoXpert Program970-000499-00
WorkstationFluoXpert Vision900-00924-00

A Complete Solution for Every Step of Your Workflow

* 24-plex kit is a customized product.