DNBSEQ-G800 Sequencer
Sequencing Without Limits
Exceptional Accuracy & Longer Reads
DNBSEQ-G800 Sequencer
Sequencing Without Limits
Exceptional Accuracy & Longer Reads
Highly Accurate
Achieve Q40 (>90%) with CoolMPS™ chemistry.
Long Read Length
Sequence up to 600 bp continuously.
Flexible
Run 2 flow cells independently & load 8 lanes individually.
G800 Sequencer Overview
DNBSEQ-G800 is a versatile benchtop sequencer designed for exceptional accuracy and extended read lengths, utilizing DNBSEQ™ technology.
Longer Reads
With Q40 accuracy and single-end reads of 600 bp or longer, it delivers the longest single read among short-read sequencers. This breakthrough is powered by CoolMPS™ technology, providing brighter and sharper imaging.
The long read length option removes barriers when sequencing challenging genomic regions, offering deeper insights into complex genetic information.
DNBSEQ-G800 is ideal for a range of applications, including:
Auto Wash Module
The DNBSEQ-G800 features an integrated auto-wash module that connects externally via a liquid line to the sequencer.
Simply insert the cleaning cartridge, and the wash cycle will automatically start immediately after sequencing.
CoolMPS™ Technology
CoolMPS™ technology utilizes nucleotides with natural bases and extension blocks, combined with labeled antibodies that are both base-specific and block-dependent.
In the traditional method, scarring—one of the main limiting factors for long-read lengths—can occur, but this issue is eliminated with the CoolMPS approach.
In the CoolMPS method, each nucleotide (dNTP) is linked to 2-4 fluorescent dyes via antibodies, resulting in higher signal intensity and much better imaging. This contributes to exceptional sequencing accuracy and reliable long-read performance.
Improved Coverage Across a Tandem Repeat Region
The SE600 long-read option on the DNBSEQ-G800 sequencer excels at sequencing challenging genomic regions that paired-end 150 sequencing struggles with. This includes tandem repeats, homopolymer stretches, and high GC content regions, as well as detecting structural variants like insertions and deletions.
The SE600 on the DNBSEQ-G800 sequencer demonstrated significantly improved coverage across a tandem repeat region compared to the PE150, providing more comprehensive and reliable data.
The SE600 demonstrated significantly improved coverage across a tandem repeat region compared to the PE150.
Streamlined WGS Workflow
Sample Prep
< 1hr
Lab Automation
Kits & Reagents
Library Prep
< 7hrs
Lab Automation
Kits & Reagents
Sequencing
48hrs
Sequencer
Kits & Reagents
Analysis
1.5hrs
Workstation
Software
Applications
| Application Type | Data Requirement | Recommend read length | # of sample per flow cell* | # of sample per run |
|---|---|---|---|---|
| Single cell RNA-Seq | 5000 cells 50K reads per cell 100 Gb per sample | PE100 | 3 | 6 |
| Transcriptomics | 40M reads/sample | PE150 | 45 | 90 |
| Targeted small panel | 1 Gb per sample | PE100 | 540 | 1080 |
| Targeted large panel | 5 Gb per sample | PE100 | 108 | 216 |
| WES | 100X sequencing depth 15 Gb per sample | PE150 | 36 | 72 |
| WGS | 30X sequencing depth 100 Gb per sample | PE150 | 5 | 10 |
| 16S | 0.1M reads per sample | SE600* | 4800 | 9600 |
* The # of sample per flow cell is calculated based on 1800M reads per flow cell except for SE600 based on 1600M reads per flow cell.
Performance Parameters
| # of Flow Cells | Reads | Read Length | Data Output (Gb) | Run Time** | Q40 |
|---|---|---|---|---|---|
| 1-2 | 1.8 – 3.6B | SE50* | 90 – 180 | 12 hrs | >90% |
| SE100* | 180 – 360 | 20 hrs | >90% | ||
| PE100 | 360 – 720 | 36 hrs | >90% | ||
| PE150 | 540 – 1080 | 48 hrs | >90% | ||
| 1.6 – 3.2B | SE600 | 960 – 1920 | 86 hrs | >80% |
* Made-to-order products **Run time refers to the duration from post-loading to sequencing completion for one or two flow cells.
Ordering Information
| Category | Product | Cat. No. |
|---|---|---|
| Instrument | DNBSEQ-G800 Genetic Sequencer | 900-000597-00 |
| Sequencing Reagents | CoolMPS High-throughput Sequencing Reagent Set (CM App-D FCL SE50) | 940-001254-00 |
| CoolMPS High-throughput Sequencing Reagent Set (CM App-D FCL SE100) | 940-001258-00 | |
| CoolMPS High-throughput Sequencing Reagent Set (CM App-D FCL PE100) | 940-001257-00 | |
| CoolMPS High-throughput Sequencing Reagent Set (CM App-D FCL PE150) 940 | 940-001250-00 | |
| CoolMPS High-throughput Sequencing Reagent Set (CM App-D FCL SE600) | 940-001733-00 |
A Complete Solution for Every Step of Your Workflow
Kits & Reagents
No matter your workflow, our kits are simple to use and easily integrated. We also offer conversion kits for 3rd party library prep.
Lab Automation
With solutions from sample extraction to lab automation you can spend less time overseeing equipment and pursue more useful activities.
