Stereo-seq Technology
Largest field of view and unbiased transcriptome at nanoscale resolution.
What is Stereo-seq Technology?
STOmics’ proprietary Stereo-seq (SpaTial Enhanced REsolution Omics-sequencing) technology provides researchers with an innovative tool for spatial biology, offering an unmatched field-of-view and subcellular resolution.
It allows simultaneous transcriptome analysis at tissue, cellular, subcellular, and molecular levels using fresh frozen tissue.
By capturing RNA information in-situ on the chip, Stereo-seq restores cellular spatial data through spatial coordination barcoding (Coordinate ID, CID). This process generates spatial gene expression profiles using the DNBSEQ™ platform, advancing research into the complex relationships between gene expression, cell morphology, and microenvironments.
Subcellular Resolution and Comprehensive
Transcriptome Analysis
Pathology and Spatio-Temporal Analysis in One Section
Our innovative staining method enables the integration of pathology study and spatio-temporal analysis on a single tissue section.
Large field of view and high resolution
Using the decimeter-scale STOmics Chip and nanoscale DNB probes, subcellular details can be captured from any location on an entire tissue section.
Multidimensional analysis
Enabled the integration of tissue staining studies with whole-genome mRNA transcriptomics and proteomics.
Excellent compatibility
Stereo-seq is compatible with fresh frozen samples and performs reliably on cells, organs, and embryo sections across various animal and plant species.
Applications
With widespread application in spatio-temporal atlases, species evolution, disease diagnosis, therapy, and prognosis, Stereo-seq and its future technical advancements promise to be transformative across multiple research fields.
This technology will deepen our understanding of human life and help redefine disease.
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